
One of the defining characteristics of hyaluronic acid dermal fillers is that they are reversible. Unlike permanent fillers or surgical procedures, HA filler can be dissolved on demand using hyaluronidase — an enzyme that breaks down hyaluronic acid into its component parts, which are then naturally cleared by the body. This reversibility is not simply a theoretical safety net: it has real and frequent practical value.
Filler results do not always meet expectations, even when placed by an experienced practitioner. Volume preferences change. Filler placed at other clinics may have drifted, overfilled or settled unevenly. Older filler from multiple treatments over the years may have accumulated and created a heaviness or distortion that no longer looks natural. In any of these situations, hyaluronidase provides a predictable, fast and effective solution.
At Elements Medical, we offer hyaluronidase treatment for patients who have had filler placed here, and equally for patients who have had filler placed elsewhere and want it corrected or removed. We approach every dissolving consultation without judgement — our goal is to assess the situation accurately and achieve the safest, most appropriate outcome for you.
Furthermore, dissolving accumulated or incorrectly placed filler before placing fresh product is increasingly considered best practice in aesthetic medicine — it allows the practitioner to start from a clean baseline and achieve a more precise, natural and predictable result than treating over existing filler allows.
We are based on Thorne Road in Doncaster with on-site parking, and we see patients from across South Yorkshire including Rotherham, Wakefield, Sheffield, Leeds and Barnsley.
Hyaluronidase — most commonly known by the brand name Hyalase — is a naturally occurring enzyme whose biological role is to break down hyaluronic acid, a glycosaminoglycan found throughout the body’s connective tissue. When injected in a purified pharmaceutical preparation into or around a deposit of HA filler, it performs this function with great efficiency — cleaving the glycosidic bonds between the HA chains and breaking the filler down into smaller fragments that the body clears through its normal metabolic processes.
How quickly does it work? Hyaluronidase begins working on injection. Most patients notice visible reduction in filler volume within minutes to hours as the enzyme acts on the deposit. The full effect — complete clearance of the filler from the treatment site — takes 24 to 48 hours as the enzyme works through the entire deposit and the breakdown products are cleared.
How is the dose calibrated? The degree of dissolving is directly proportional to the dose of hyaluronidase administered. A conservative dose produces partial volume reduction; a higher dose achieves complete elimination of the filler. This dose-dependent response allows precise control of the outcome — your practitioner will discuss whether partial correction or full elimination is the goal at your consultation, and administer accordingly.
What about firmer fillers? Firmer, higher-cohesivity fillers — typically used for structural areas like the cheeks, jawline and chin — have longer and more cross-linked HA chains and consequently require more hyaluronidase to dissolve fully. Your practitioner will account for this in the dose. Multiple sessions are occasionally needed for dense or long-standing filler deposits.
What hyaluronidase cannot dissolve: Hyaluronidase acts only on hyaluronic acid. It has no effect on non-HA fillers such as calcium hydroxylapatite (Radiesse), poly-L-lactic acid (Sculptra) or any permanent filler. If you are uncertain whether your filler is HA-based, your practitioner will assess this at consultation.
The clinical evidence for hyaluronidase as a safe and effective reversal agent for hyaluronic acid dermal filler is well established in the peer-reviewed literature. British Journal of Dermatology — hyaluronidase and filler reversal
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The primary purpose of hyaluronidase treatment is to return the tissue to its natural pre-treatment state — safely, predictably and without permanent consequences — when a filler result is not what was wanted. Whether the issue is incorrect placement, excessive volume, unevenness, migration or simply a change in personal preference, dissolving provides a genuine reset that restores the patient’s autonomy over their own appearance and creates a clear path forward, whether that means leaving the area natural or proceeding with a fresh, correctly approached treatment.
In the rare but serious event of vascular compromise associated with filler — where product enters or compresses a blood vessel — hyaluronidase administered promptly and in high dose is the primary emergency intervention that can restore blood flow and prevent permanent tissue damage. Beyond emergency use, timely hyaluronidase treatment is also the appropriate management for vascular occlusion symptoms, significant nodule formation, Tyndall effect and infection-associated filler. Consequently, access to a clinic that can perform hyaluronidase treatment promptly is an important consideration for any patient who has had HA filler placed.
Accumulated filler — particularly in the lips, cheeks and tear trough from repeated treatments over several years — can create a heaviness, structural distortion or loss of natural movement that worsens progressively. Dissolving the accumulated product before fresh filler is placed allows the practitioner to start from an accurate baseline, use precisely calibrated amounts and achieve a more refined, natural and predictable result than treating over existing product allows.
1. Rapid and predictable reversal of hyaluronic acid filler Hyaluronidase begins working on injection and produces visible filler reduction within hours, with full clearance within 24 to 48 hours — the fastest and most predictable method of reversing any HA filler result.
2. Suitable for all facial areas where HA filler has been placed Hyaluronidase dissolves HA filler in the lips, cheeks, tear trough, jawline, chin, nose, temples and any other facial area — regardless of where the original treatment was performed.
3. Dose-dependent control allows selective reduction or complete elimination The degree of dissolving is directly related to dose — allowing selective partial correction where complete elimination is not the goal.
4. The essential safety tool for vascular complications In the event of vascular compromise, prompt high-dose hyaluronidase is the primary emergency treatment. Access to a clinic that holds and can administer hyaluronidase is a critical patient safety consideration.
5. No permanent consequences — tissue returns to its natural state HA filler dissolved with hyaluronidase leaves no permanent change to the tissue, which returns to its natural baseline within 24 to 48 hours.
6. Creates a clean baseline for fresh, more precisely calibrated filler treatment Dissolving accumulated or incorrectly placed filler before fresh treatment allows greater precision, a more natural result and a more accurate assessment of the volume and placement needed.
7. Available for filler placed anywhere — not only at Elements Medical Patients who have had filler placed at other clinics and are unhappy with the result, experiencing complications, or simply wish to start again are welcome for assessment and treatment at Elements Medical.
Overfilled or Uneven Lips
Lip filler that has produced excessive volume, an uneven shape, a duck-like forward projection or a heavy, unnatural result is the most common presentation for dissolving treatment. Hyaluronidase dissolves the existing product and returns the lips to their natural state, after which fresh filler can be placed — or the lips left natural — according to the patient’s preference. Our dissolve and redesign package (£280) covers both the dissolving session and 1ml of fresh lip filler four weeks later.
Migrated or Lumpy Filler
Filler that has moved from its original placement, formed palpable lumps or nodules, or created a visible ridge — most commonly seen in the lip border zone — benefits from dissolving to break down the irregular deposit and allow the tissue to reset naturally before any fresh treatment.
Tear Trough Tyndall Effect and Complications
The tear trough is one of the highest-risk areas for filler complications including Tyndall effect (a blue-grey discolouration visible through the thin under-eye skin), puffiness and lumpiness from product placed too superficially or in excessive volume. Hyaluronidase is the standard treatment for these complications and is frequently used to clear existing tear trough filler before a fresh, correctly approached result.
Accumulated Filler From Multiple Treatments
Patients who have had repeated filler over several years — particularly in the cheeks, lips or tear trough — may find the accumulated product has created a heaviness or distortion that no longer looks natural. Dissolving to a clean baseline before conservative, precisely placed fresh filler consistently produces a more natural and proportionate result.
Personal Preference or Change of Mind
Patients who simply want to return to their natural appearance, feel that filler no longer suits them, or have changed their aesthetic preferences are welcome for dissolving treatment. Patient preference alone is a valid reason — no complication or error needs to have occurred.
HA filler does degrade naturally over time through the body’s own hyaluronidase activity and metabolic processes — but the timeline is considerably longer than most patients expect, and varies significantly between individuals and products.
Soft tissue lip fillers typically last 9 to 12 months in most patients. Firmer, higher-cohesivity structural fillers used in the cheeks, jawline and chin can persist for two to three years or more. Waiting for natural degradation is a reasonable option when the result is only mildly unsatisfactory. However, if the filler is causing distress, a visible complication, or preventing fresh treatment from being planned, hyaluronidase offers an immediate and reliable solution — rather than months of unwanted results.
At Elements Medical, dissolving dermal filler is performed by experienced practitioners who approach every case with care, thoroughness and the absence of judgement — whether the original treatment was performed at our clinic or elsewhere. Our priority in every dissolving consultation is the safest and most appropriate outcome for the patient.
Every dissolving consultation includes a thorough assessment of the filler, a discussion of the desired outcome and the mandatory patch test. We do not proceed with hyaluronidase treatment without a completed patch test, and we do not rush the consultation or the treatment.
For patients considering fresh filler treatment following a dissolve, see our full dermal filler treatments range, including lip enhancement, cheek filler, tear trough filler and the Elements Liquid Lift.
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30 minutes
Instant
Swelling and bruising can occur, and some mild discomfort
Minimal
The next day depending on side effects
A dental block will be administered to make sure the area is completely numb to make treatment as comfortable as possible
Hyaluronidase (Hyalase) is an enzyme that breaks down hyaluronic acid — the primary component of most dermal fillers — by cleaving the bonds that hold the HA chains together. When injected into or around a filler deposit, it begins working immediately, breaking the filler into fragments that the body clears naturally. The full dissolving effect takes 24 to 48 hours.
Hyaluronidase is animal-derived (bovine or ovine origin) and carries a small but documented risk of allergic reaction, including rare anaphylaxis. A mandatory intradermal patch test — a small injection on the inner forearm, observed for 20 to 30 minutes — is performed before every dissolving treatment to screen for allergic sensitivity. This is a patient safety requirement that we do not waive. The patch test is typically completed at the same appointment as your consultation, so both can be done in a single visit.
Yes. We regularly see patients whose filler was placed elsewhere. We approach every dissolving consultation without judgement and our only concern is the safe and appropriate management of your situation.
We advise waiting at least 2 weeks after your original filler treatment. This allows post-treatment swelling to fully subside so you are dissolving the accurate settled result rather than swollen tissue.
We advise waiting at least 4 weeks after dissolving before having fresh filler placed. This allows the hyaluronidase to fully clear, residual swelling to resolve and the area to return to its natural baseline before new product is introduced.
In most cases, dissolving HA filler returns the tissue close to its pre-treatment state. The result may not be identical to before filler was ever placed — particularly with long-standing filler, multiple accumulated treatments, or in the immediate post-dissolving period when some swelling is present. Your practitioner will discuss realistic expectations at consultation.
For lip and perioral dissolving, a dental block ensures the area is completely numb before treatment. For other areas, topical anaesthetic cream is applied. Most patients find the treatment very comfortable after anaesthetic has taken effect.
No — only hyaluronic acid fillers. It has no effect on non-HA fillers such as Radiesse (calcium hydroxylapatite), Sculptra (poly-L-lactic acid) or permanent fillers. If you are unsure whether your filler is HA-based, your practitioner will assess this at consultation.
The dissolve and redesign package (£280) covers your full dissolving session plus 1ml of fresh lip filler at a follow-up appointment four weeks later — the appropriate option for patients who are unhappy with their existing lip filler and want to start again with a fresh, correctly approached result.
Minimal. Swelling and bruising in the dissolved area typically resolve within a few days. Most patients return to normal activities the following day. The area may feel tender for 24 to 48 hours.
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Complete Your Forms
Your medical history form will be emailed for you to complete before you attend.
Select Your Treatment
Browse through our website and choose the treatment that’s right for you.
Book Online or Call Us
Follow the link below to book your treatment online. Or call us on 01302 34 34 32
Complete Your Forms
Your medical history form will be emailed for you to complete before you attend.
Call us: 01302 34 34 32
Email us: reception@elements.org.uk
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