
The plasma resurfacing category has expanded significantly over the past decade, and NeoGen Plasma Skin Regeneration (PSR) technology remains its most clinically validated and versatile representative. Its fundamental advantage over laser-based resurfacing is the mechanism by which it delivers thermal energy to the skin: where lasers rely on chromophore absorption — targeting water, melanin or haemoglobin at specific wavelengths — plasma delivers its thermal energy through ionisation of nitrogen gas, independent of skin colour or melanin content. This is the reason NeoGen is safe and effective across all Fitzpatrick skin types, including types V and VI where CO2 laser resurfacing carries a significantly elevated risk of post-inflammatory hyperpigmentation.
The second distinguishing feature of NeoGen is its variable energy range. At lower energy settings the treatment is minimally ablative, producing a collagen-stimulating thermal response with one to three days of visible redness and dryness. At higher energy settings the treatment becomes fully ablative, with the plasma energy destroying the outer skin layers and producing a wound-healing and collagen remodelling response comparable in depth and impact to CO2 fractional laser — with a seven to ten day recovery. This energy scalability means NeoGen can serve as both a progressive low-downtime skin quality programme and a single high-impact resurfacing treatment, depending entirely on what is most appropriate for the patient.
At Elements Medical our practitioners are experienced in calibrating NeoGen treatment parameters to match each patient’s skin type, concern severity and downtime tolerance, and will discuss the appropriate energy level and treatment plan in full at consultation.
Our Doncaster clinic is on Thorne Road with on-site parking, and we welcome patients from across South Yorkshire including Rotherham, Wakefield, Sheffield, Leeds and Barnsley.
NeoGen PSR (Plasma Skin Regeneration) uses a handpiece that converts medical-grade nitrogen gas into plasma — an ionised, high-energy state of gas — and delivers this plasma energy to the skin surface in precise, controlled pulses.
When nitrogen plasma contacts the skin, it converts its energy to heat on contact, creating a controlled thermal effect throughout the full depth of the treated skin. This is a fundamental difference from fractional laser devices, which create their thermal zones in a grid pattern leaving intervening tissue intact. NeoGen plasma treats the full surface of the skin uniformly — the entire treated area receives the thermal stimulus simultaneously, rather than fractionally.
What happens at low energy: At lower energy settings, the thermal effect stimulates a collagen and elastin remodelling response in the dermis without fully destroying the epidermal layer. The surface of the skin may experience mild dryness and peeling as the outer layers turn over, but the skin surface remains largely intact as a natural biological dressing. Downtime is minimal — typically one to three days of redness and dryness — and treatment can be repeated as a course for progressive improvement.
What happens at high energy: At higher energy settings, the full thermal effect reaches a level at which the outer skin layers are ablated — destroyed and replaced. The skin surface separates over the following days as new, regenerated skin forms beneath it. The wound-healing response at this energy level produces a deeper and more significant collagen remodelling response, with results and recovery comparable to ablative CO2 laser resurfacing. Downtime is seven to ten days.
The biological response in both cases: Regardless of energy level, the thermal stimulus from NeoGen treatment activates fibroblasts to produce new collagen and elastin, triggers cellular regeneration in the dermis, and produces a progressive improvement in skin quality, firmness, texture and tone as the treated tissue remodels over four to twelve weeks following treatment.
The clinical evidence for plasma skin regeneration technology in collagen remodelling, pigmentation and skin rejuvenation is supported by peer-reviewed research. British Journal of Dermatology — plasma skin regeneration
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1. Restoring Skin Structure and Quality Through Deep Plasma-Driven Regeneration
NeoGen Plasma produces one of the most comprehensive skin regeneration responses available in non-surgical aesthetics — triggering simultaneous renewal of the epidermis, activation of deep dermal fibroblasts and collagen synthesis, and remodelling of the full skin architecture in a single treatment. For patients with significant skin quality concerns, wrinkling, laxity, scarring or photodamage, the combination of full-surface thermal treatment and scalable energy levels means NeoGen can be calibrated to deliver the precise depth of restoration that each individual concern requires — from a progressive resurfacing programme to a single high-impact session. The restored collagen is new, structurally sound and genuinely improves both the appearance and the physical quality of the skin.
2. Maintaining Skin Health Through Sustained Collagen Remodelling
The collagen remodelling response triggered by NeoGen treatment is not immediate — it builds and matures for four to twelve weeks following each session, and the structural improvement in skin quality continues to develop for months. Low-energy maintenance sessions sustain the elevated level of dermal collagen and skin quality that a course achieves, protecting the skin against the ongoing collagen loss of ageing and keeping the skin in the best structural condition achievable without surgery. This is particularly meaningful for patients who have invested in a high-energy resurfacing session and want to preserve and build on the result over time.
3. Protecting Confidence and Psychological Wellbeing Through Inclusive, Visible Improvement
One of the most important aspects of NeoGen Plasma as a treatment option is its inclusivity — the fact that it is safe and effective across all skin types, including those where many of the most powerful resurfacing options are contraindicated or carry elevated risk. For patients with darker complexions who have been told they are not suitable for laser resurfacing, NeoGen represents a genuinely accessible route to the quality of improvement that advanced resurfacing can provide. The confidence that comes from being able to address a significant skin concern — one that may have been long-standing and previously felt untreatable — is profound.
1. Safe and effective across all skin types including Fitzpatrick types V and VI Because nitrogen plasma delivers thermal energy independently of melanin content — without the chromophore-selective mechanism of lasers — NeoGen treats all skin types with comparable safety and efficacy, including darker tones where ablative CO2 laser carries a significantly elevated risk of post-inflammatory hyperpigmentation.
2. Scalable energy levels from minimal to maximum downtime NeoGen’s variable energy range spans from a low-energy, minimal-downtime collagen-stimulating treatment to a high-energy fully ablative session with seven to ten days of recovery — enabling the same device to serve different patients, concerns and downtime tolerances.
3. Full-surface treatment without fractional sparing Unlike fractional laser devices, NeoGen plasma treats the full surface of the skin uniformly in each pass, producing an even and comprehensive thermal stimulus across the entire treatment area.
4. Stimulates deep, sustained collagen remodelling The thermal response activates fibroblasts throughout the full depth of the dermis, triggering a sustained collagen and elastin synthesis response that continues to develop and mature for four to twelve weeks post-treatment.
5. Achieves results comparable to ablative CO2 laser at high energy At high energy settings, NeoGen produces a wound-healing and collagen remodelling response comparable to CO2 fractional laser resurfacing in terms of depth and clinical outcome — but without the melanin-targeting mechanism that makes CO2 higher risk in darker skin tones.
6. Treats the full face, neck, chest and eye area NeoGen is safe for use on all facial areas including the delicate periorbital zone, and extends effectively to the neck and chest for comprehensive rejuvenation across multiple areas in a single session.
7. Results develop progressively for months after treatment The initial visible improvement that appears as healing completes is only the beginning — collagen remodelling continues for four to twelve months post-treatment, with patients experiencing ongoing improvements in firmness, texture and overall skin quality throughout.
Fine Lines and Wrinkles NeoGen produces a significant reduction in fine lines and wrinkles through deep dermal collagen stimulation and skin surface renewal. Particularly effective for perioral lines, periorbital wrinkling and overall facial rhytids.
Skin Laxity and Loss of Firmness The sustained collagen and elastin remodelling progressively tightens lax, crepey skin across the face, neck and chest. At higher energy levels, NeoGen produces a quality of skin tightening that reflects a genuine structural improvement in the dermal matrix.
Pigmentation, Sun Damage and Uneven Skin Tone Full-surface thermal treatment addresses epidermal pigmentation by accelerating the turnover of melanin-containing cells. Sun spots, photodamage and general uneven tone all respond well, with progressive improvement in skin clarity and evenness across a course.
Acne Scarring NeoGen produces meaningful improvement in acne scarring through epidermal renewal and deep dermal collagen remodelling. It is effective across atrophic scar subtypes and is a particularly strong option for patients with darker skin who are not suitable for ablative CO2 laser.
Overall Skin Quality and Rejuvenation For improved radiance, clearer tone, refined texture and firmer, structurally healthier skin, NeoGen Plasma at either a progressive low-energy course or a single high-energy session produces a quality of overall skin transformation that is difficult to achieve through non-resurfacing approaches.
Periorbital Area and Eye Surround NeoGen is safe for use in the periorbital area, suitable for fine lines, crepiness and skin quality concerns around the eyes. Available as part of the overall face treatment or as a standalone eye area session.
CO2 fractional laser resurfacing and NeoGen Plasma are the two most powerful resurfacing treatments available at Elements Medical, sitting at a comparable tier of clinical intensity at high energy.
CO2 laser uses laser light at a specific wavelength absorbed by water in the skin tissue, creating its ablative effect through selective photothermolysis and delivering it in a fractional grid pattern. NeoGen uses ionised nitrogen plasma, which converts its energy to heat on contact with the full skin surface uniformly, independent of chromophore targets.
The practical implication is skin type suitability. CO2 laser’s chromophore interaction creates a meaningful risk of post-inflammatory hyperpigmentation in Fitzpatrick types IV to VI. NeoGen does not interact with melanin in the same way, making it a safer option for these skin types. For Fitzpatrick types I to III, both treatments are appropriate and the choice is based on other factors.
Both produce comparable results at high energy for wrinkle reduction, acne scar improvement and overall rejuvenation. Your practitioner will discuss the most appropriate option for your skin type and concern at consultation.
LaseMD is a non-ablative thulium fibre laser with one to three days of downtime at all treatment levels, suited to pigmentation, uneven skin tone, general skin quality improvement and mild to moderate concerns.
NeoGen Plasma spans a much broader energy and intensity range — from a low-energy treatment similar in downtime to LaseMD, through to a fully ablative high-energy session with seven to ten days of recovery and outcomes comparable to CO2 laser. NeoGen is the appropriate choice when more significant concerns — laxity, deeper wrinkles, acne scarring, substantial photodamage — require a higher-intensity resurfacing response.
In practical terms: if your concern is mild to moderate and your priority is minimal downtime, LaseMD is usually the right place to start. If your concern is more significant and you are prepared for a meaningful recovery window, NeoGen Plasma at higher energy offers a step-up in clinical impact that LaseMD does not match.
Radiofrequency microneedling (RFM) delivers radiofrequency energy into the dermis via insulated needles, producing a collagen remodelling and skin tightening response with one to three days of downtime. RFM and NeoGen low-energy treatment are broadly comparable in downtime and type of improvement.
The key differences: RFM excels at skin tightening and structural remodelling through direct dermal energy delivery. NeoGen also produces surface renewal — the epidermal turnover that improves pigmentation, overall radiance and skin clarity — which RFM does not.
For patients with significant surface concerns alongside tightening requirements, NeoGen covers both dimensions in a single treatment. For patients whose primary concern is tightening without significant surface-level issues, RFM may be equally effective with a more targeted mechanism.
NeoGen Plasma’s variable energy range means that calibration of treatment parameters is central to achieving the right outcome for each patient. At Elements Medical, every NeoGen treatment is preceded by a thorough consultation in which your skin type, concerns and recovery tolerance are assessed, and the appropriate energy level and treatment plan are agreed before any treatment takes place
We offer NeoGen Plasma as part of a complete resurfacing and regenerative range that also includes CO2 laser, LaseMD and radiofrequency microneedling, and will always recommend the treatment that is genuinely the right match for your skin, your goals and your downtime tolerance.
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Approximately 30 to 60 minutes, depending on the area being treated and the energy level selected.
Visible improvements may appear within a few days, with continued skin regeneration and enhanced results developing over 4 to 12 weeks. Collagen production continues for months post-treatment.
You may experience mild redness, warmth, tightness, or flaking in the treated area. These are normal and typically resolve within a few days. In rare cases, swelling or pigmentation changes may occur.
Downtime depends on treatment intensity: Low energy: Minimal downtime (1–3 days of mild redness or dryness) High energy: Moderate downtime (up to 7–10 days of visible healing)
Most patients return to normal activities within 1–3 days after a low-energy treatment. Higher-energy treatments may require a few more days for social downtime.
Topical anaesthetic applied 30 min prior to treatment
NeoGen Plasma (PSR — Plasma Skin Regeneration) is a medical-grade skin resurfacing technology that uses ionised nitrogen gas — plasma — to deliver controlled thermal energy to the skin. This triggers a powerful collagen remodelling and regeneration response that improves skin quality, firmness, texture, pigmentation and scarring. Unlike laser devices, it does not rely on chromophore targeting, making it safe and effective across all skin types including darker Fitzpatrick tones.
Both, depending on the energy level used. At low energy settings, NeoGen produces a collagen-stimulating thermal response with minimal surface disruption — similar in character to a non-ablative treatment, with one to three days of downtime. At high energy settings, NeoGen is ablative: the plasma energy reaches a level at which the outer skin layers are destroyed and replaced, producing a wound-healing and collagen remodelling response comparable to CO2 laser resurfacing, with seven to ten days of recovery. The appropriate energy level for each patient is determined at consultation.
NeoGen is safe and effective across all Fitzpatrick skin types, including types V and VI. Because nitrogen plasma delivers its thermal effect independently of melanin content — without the chromophore-selective mechanism of lasers — it does not carry the elevated risk of post-inflammatory hyperpigmentation that makes ablative CO2 laser unsuitable for darker skin tones. This is one of NeoGen’s most important clinical advantages.
NeoGen Plasma treats fine lines and wrinkles, skin laxity and crepiness, pigmentation and sun damage, acne scarring, enlarged pores, overall skin quality and radiance, and periorbital skin concerns. It is effective across the face, neck, chest and eye area.
This depends on the energy level used and your concerns. Low-energy treatment is typically delivered as a course of three to six sessions at three to four week intervals, with progressive improvement across the course. High-energy treatment typically requires one to two sessions with a longer interval between them to allow full healing and collagen remodelling. Your practitioner will recommend the appropriate programme at consultation.
Downtime depends on the energy level. Low-energy treatment produces one to three days of mild redness and possible dryness or peeling. High-energy treatment produces seven to ten days of visible healing — significant redness and warmth in the first 48 hours, followed by the gradual separation of the treated skin surface over days four to seven as new skin forms underneath. This is an expected and normal part of the regeneration process at high energy.
Topical anaesthetic cream is applied before treatment to ensure comfort. Most patients find low-energy NeoGen treatment very tolerable. High-energy sessions require more effective anaesthesia and patients typically experience warmth and some discomfort during the procedure, which subsides once the treatment is complete.
Initial visible improvement in skin quality, texture and radiance appears as the healing phase completes — within a few days for low-energy treatment and at seven to ten days for high-energy. Deeper collagen remodelling continues to develop for four to twelve weeks post-treatment, with patients experiencing ongoing improvements in firmness, clarity and overall skin quality throughout this period. Results can continue to mature for up to twelve months.
Results from NeoGen treatment typically last twelve months or longer, depending on energy level, number of sessions and skincare maintenance. The collagen remodelling response continues to produce improvements for several months post-treatment. Daily broad-spectrum SPF use is essential to protect the results from UV-driven degradation.
Yes. NeoGen is safe for use in the periorbital area and is available as a targeted eye treatment for fine lines, crepiness and skin quality concerns around the eyes. This is an area where many resurfacing technologies carry increased risk; NeoGen’s controlled plasma delivery is well tolerated in this delicate zone.
CO2 laser uses a specific wavelength laser that targets water in skin tissue and is delivered fractionally — treating columns of tissue while leaving intervening tissue intact. Its interaction with melanin creates a higher risk of PIH in darker skin tones. NeoGen uses nitrogen plasma to treat the full skin surface uniformly, independent of melanin content, making it safe across all skin types. Both produce comparable clinical outcomes at high energy in terms of wrinkle reduction, scarring improvement and overall rejuvenation.
Yes. NeoGen Plasma combines well over time with polynucleotides, PRF treatment and exosome therapy to support post-treatment collagen maturation and accelerate healing. It is also complementary to skin boosters for maintaining skin hydration and quality between resurfacing sessions. Timing and sequencing of combination treatments are discussed at consultation.
NeoGen Plasma treatment is not recommended during pregnancy or breastfeeding.
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Select Your Treatment
Browse through our website and choose the treatment that’s right for you.
Book Online or Call Us
Follow the link below to book your treatment online. Or call us on 01302 34 34 32
Complete Your Forms
Your medical history form will be emailed for you to complete before you attend.
Call us: 01302 34 34 32
Email us: reception@elements.org.uk
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